About Targeted Treatment

A targeted treatment is a type of medicine that is aimed at certain traits in a tumor cell that try to make it stop growing or die. These medicines might block a signal that tells the cells to grow and divide without control. This may help to keep the tumor from growing and spreading to other parts of the body.1

There are targeted treatments for some biomarkers. By testing tumors, your doctor may know if a targeted therapy is right for your tumor type.1

Determining if a Treatment Works

In some cancers, biomarkers may be used to see if the treatment is working. If there is a biomarker in the tumor, then doctors can test how much of it is present to see if the treatment is taking effect.2

If a biomarker level goes down, then it may be a sign that the drug is working. If the biomarker level goes up, then that might be a sign that the drug is not working on that cancer. In that case, the doctor may need to change or adjust the treatment or the dose.3

Doctors can also test tumors after treatment, even years later. This helps to find out if the cancer has returned (or recurred).2

References:
  1. National Cancer Institute. Targeted Cancer Therapies. Available at http://www.cancer.gov/cancertopics/factsheet/Therapy/targeted. Accessed April 1, 2011.
  2. National Cancer Institute. Tumor Markers: Questions and Answers. Available at http://www.cancer.gov/cancertopics/factsheet/detection/tumor-markers. Accessed April 1, 2011.
  3. American Cancer Society. Tumor Markers Fact Sheet. Available at http://www.cancer.org/acs/groups/cid/documents/webcontent/003189-pdf.pdf. Accessed March 31, 2011.

See a guide to discussing biomarkers and cancer care with your doctor.

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Learn about the specific roles the members of a medical team play in cancer treatment.

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